Mitocondria

... mutations and nuclear genomes within it. This mutation was first seen in a person who suffered from hypermetabolism. They had a large amount of infected mitochondria in there body. Scientist looked at this and decided that this was what was causing the problems. This was the first time scientist were able to prove mitochondria was the cause for a disease. “Mutations in the mitochondrial DNA have been associated with mitochondrial disease and many mutations have been identified” (Ichizo Nishino, et al., 1999). This says that the mitochondrial DNA is being mutated and causes the cell to go bad. These mitochondria are related to prions. They are both parts in the cell that are used to help the body, that have gone bad. With prions it was with the proteins, while mitochondrial disease is with the mitochondria. We next look at how the mitochondrial mutations are transferred to other mitochondria. “It has been thought that inheritance of mitochondria is a passive process” (Yaffe, 1999). This was thought to happen because of the diffusion that takes place in the cell. Scientists later realized this is not how the mitochondrial inheritance takes place. “A recognition of morphology, the association with the cytoskeleton, and movements of the mitochondria during cell...

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