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In 1936, an English scientist, Sir Henry Hallett Dale and his friend and colleague, Otto Loewi were awarded the Nobel Prize for Physiology or Medicine for their work which showed that nerve impulses were transmitted by chemical signals. ...
Up until 1921, it was generally thought that an organ’s function was affected by direct transmission of the stimulation from the nerve fiber. The possibility of chemical transmission became an experimental reality in Loewi’s laboratory. ... One heart was connected to the vagus nerve and was placed in a chamber filled with saline. ... Electrical stimulation of the vagus nerve caused the first heart to slow down. ... Hence, Loewi hypothesized that electrical stimulation of the vagus nerve released a chemical into the fluid of first chamber that flowed into the second chamber. He named the chemical “Vagusstoff”. ... How about chemical transmission of nerves in sympathetic system? ... Sir Henry and colleagues discovered that stimulation of certain nerve fibers which belong anatomically to the sympathetic system lead to the release of acetylcholine in a large number of cases.
Approximate Word count = 724
Approximate Pages = 2.9
(250 words per page double spaced)
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