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Nerve Action Potentials and Sensory Physiology
Lab Report
Question #1
Calculate the potassium equilibrium potential for [K]o = 5mM and for [K]o = 12. ... Compare these equilibrium potentials with the membrane potential in the simulations. ... Compare these equilibrium potentials with the membrane potential in the simulations. ...
Question #5
Label the following parts of the action potential: depolarizing phase, overshoot, repolarizing phase, undershoot. Estimate the threshold potential for triggering an action potential.
Question #6
Why is the size of the action potential so much smaller when external sodium concentration is reduced?
During the depolarizing phase of the action potential, the voltage-sensitive sodium channel opens and the influxes of sodium ion takes place. Those influxes bring the membrane potential to be depolarized, which result the action potential. ... Smaller concentration of sodium means smaller number of sodium ions to depolarize the action potential. Thus, it would bring the size of the action potential so much smaller. ... Explain why an action potential is triggered by injecting positive current into a neuron, but not by injecting negative current. ... Action potential is triggered by the depolarization by positive charges and so injecting negative current would direct the membrane potential towards opposite way in terms of action potential.
Approximate Word count = 963 Approximate Pages = 3.9 (250 words per page double spaced)
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