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... The name of this enzyme is acetylcholinesterase. ... With assistance from two of their pupils, Thomas Renton Elliot, and Walter Dixon, they came to a conclusion about a single chemical nerve transmitter (which would later be referred to as acetylcholinesterase). ... Eventually, after experimenting on various test patients, they discovered the presence of acetylcholinesterase. ...
Acetylcholinesterase (AChE), more commonly known as “true” cholinesterase, is an enzyme of the hydrolases class that catalyses the cleavage of acetylcholine and water to choline and acetate (see fig. ... Acetylcholinesterase’s biological role, is the termination of impulse transmissions at cholinergic synapses within the nervous system via the rapid hydrolysis of the neurotransmitter, acetylcholine, (Jubeck, 1999). ... At this point, the acetylcholinesterase enzyme attaches itself to the substrate acetylcholine, destroying the molecule and closing the ion channels. ...
Like most enzymes, acetylcholinesterase exists in various numbers from person to person. ...
Like most enzymes, acetylcholinesterase has optimum conditions at which it works best. ... In Canada, there are only four Acetylcholinesterase inhibitors that have been approved by the FDA, these include Tacrine, Donepezil HCL, Rivastigamine and Galantamine. ...
Without the acetylcholinesterase enzyme, it would be impossible for mammals, and many others animals to send neural transmissions to the rest of the body.
Approximate Word count = 1323
Approximate Pages = 5.3
(250 words per page double spaced)
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