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Crohn’s Disease
Crohn’s disease was named after an 1884 physician by the name of Burrill B. ... He was the first of a three author landmark paper written in 1932 describing the disease. Crohn’s disease is a disorder of the gastrointestinal tract that is characterized by inflammation and deep ulcer formation n the lining of any region of the tract from the mouth to the anus. It is also more commonly referred to as inflammatory Bowel Disease (IBD), the general name for diseases that cause inflammation in the intestines.
The cause of Crohn’s disease is unknown; it affects men and women equally. Some scientists suspect that infection by certain bacteria, such as strains of mycobacterium, may be the cause of Crohn’s disease. To date, there has been no convincing evidence that the disease is caused by infection. Crohn’s disease is not contagious. Although diet may affect the symptoms in-patients with Crohn’s disease, it appears unlikely that diet is responsible for the onset of the disease. ... In-
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patients with Crohn’s disease, the immune system seems to react actively to a variety of substances and/or bacteria in the intestines, causing inflammation, bowel injury, and ulcerations. ... First degree relatives of patients with Crohn’s disease (brothers, sisters, sons and daughters) are more likely to develop the disease. Furthermore, certain chromosome markers have been found in-patients with Crohn’s disease. ... Children with the disease often suffer delayed development and stunted growth. ... The pain of Crohn’s disease can also be crampy in nature, and may reflect bowel obstruction. ... Disease affecting the anus is common. Up to one third of patients with Crohn’s disease may have diseases involving the anal area. ... As the disease progresses, the bowel becomes increasingly narrowed, and ultimately can become obstructed. ... When Crohn’s disease narrows the small intestine to the point of obstruction, the flow of the contents through the intestine ceases. ...
Crohn’s disease can be difficult to diagnose because its symptoms are similar to other intestinal disorders such as IBD and ulcerative colitis, which is another form of IBD. ... A thorough physical exam and a series of tests may be required to diagnose Crohn’s disease. ... The doctor may do Barium x-ray studies to define the distribution, nature, and severity of the disease. ... During the exam, the doctor may do a biopsy, which involves taking a sample of tissue from the lining of the intestine to view with a microscope to confirm the diagnosis of Crohn’s disease. ... Most recently, video capsule endoscopy has been added to the list of diagnostic tests for diagnosing Crohn’s disease. ... The value of the video capsule endoscopy is that it can identify the early, mild abnormalities of Crohn’s disease.
Approximate Word count = 2265
Approximate Pages = 9.1
(250 words per page double spaced)
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